Book Lee County Hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
11 Dec - 12 Dec
Tomorrow
12 Dec - 13 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Lee County hotels

Lobby sitting area
Cobblestone Inn & Suites - Fort Madison

Cobblestone Inn & Suites - Fort Madison

Cobblestone Inn & Suites - Fort Madison
2.5 star property
Fort Madison
9.4 out of 10, Exceptional, (646)
"Always love staying here while visiting family. Very clean and comfortable beds "
United States
Jessica
The price is AU$125
includes taxes & fees
16 Dec - 17 Dec
Cobblestone Inn & Suites - Fort Madison
Indoor pool, open 7:00 AM to 11:00 PM, pool loungers
Quality Inn & Suites Keokuk North

Quality Inn & Suites Keokuk North

Quality Inn & Suites Keokuk North
2.5 star property
Keokuk
8.4 out of 10, Very good, (749)
"Great staff! Clean hotel!"
United States
Matthew
The price is AU$131
includes taxes & fees
11 Jan - 12 Jan 2026
Quality Inn & Suites Keokuk North
Lobby
Quality Inn & Suites Fort Madison near Hwy 61

Quality Inn & Suites Fort Madison near Hwy 61

Quality Inn & Suites Fort Madison near Hwy 61
2.5 star property
Fort Madison
8.6 out of 10, Excellent, (570)
"Quiet, large parking lot, restaurant next door, free breakfast was good, hot tub and pool very nice. "
United States
Audrey
The price is AU$132
includes taxes & fees
11 Jan - 12 Jan 2026
Quality Inn & Suites Fort Madison near Hwy 61
Free daily on-the-go breakfast
Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk

Baymont by Wyndham Keokuk
2.5 star property
Keokuk
6.2 out of 10, (489)
"Great location for geode hunting. Irish Pub behind the hotel is the best."
United States
Marty
The price is AU$93
includes taxes & fees
11 Jan - 12 Jan 2026
Baymont by Wyndham Keokuk
Indoor pool, open 6 AM to 11 PM, pool loungers
Hampton Inn Keokuk

Hampton Inn Keokuk

Hampton Inn Keokuk
2.5 star property
Keokuk
8.8 out of 10, Excellent, (640)
"Very good stay. I’ll definitely stay there again "
United States
Tammy
The price is AU$153
includes taxes & fees
2 Jan - 3 Jan 2026
Hampton Inn Keokuk
Lobby
Super 8 by Wyndham Fort Madison

Super 8 by Wyndham Fort Madison

Super 8 by Wyndham Fort Madison
2.0 star property
Fort Madison
6.8 out of 10, (324)
"I would definitely stay there again!"
United States
Marcia
The price is AU$108
includes taxes & fees
12 Dec - 13 Dec
Super 8 by Wyndham Fort Madison
Exterior
Rivers Inn Fort Madison

Rivers Inn Fort Madison

Rivers Inn Fort Madison
2.0 star property
Fort Madison
6.2 out of 10, (165)
"Wonderful lady at desk, quite place,not far from town have been here several times and will be back"
United States
lance
The price is AU$80
includes taxes & fees
18 Dec - 19 Dec
Rivers Inn Fort Madison
Standard Single Room, 1 King Bed | Living area
Budget Inn

Budget Inn

Budget Inn
2.0 star property
Keokuk
8.0 out of 10, Very good, (71)
"Friendly front desk staff and accommodating."
United States
Guillermo
The price is AU$101
includes taxes & fees
12 Dec - 13 Dec
Budget Inn
Luxury Suite, 1 King Bed with Sofa bed, River View | Living area
Kingsley Inn

Kingsley Inn

Kingsley Inn
3.5 star property
Fort Madison
9.2 out of 10, Wonderful, (485)
"Excellent accommodation, beautiful hotel! Checking with code was good! Great place to watch trains!"
United States
Gerald
Kingsley Inn
Standard Room, 2 Double Beds
Chief Motel

Chief Motel

Chief Motel
2.5 star property
Keokuk
7.8 out of 10, Good, (111)
"The daily cleaning and room care amazed us. Totally over the top service. "
United States
Robert
The price is AU$101
includes taxes & fees
12 Dec - 13 Dec
Chief Motel
Exterior
Johnstone Mansion

Johnstone Mansion

Johnstone Mansion
3.0 star property
Keokuk
8.4 out of 10, Very good, (5)
"Absolutely loved this beautiful restored old world home! We could walk around and look at the amazing Victorian interior and furnishings for days. Peter was an amazing host and we hope to come back to visit some day. "
United States
Darlene
The price is AU$318
includes taxes & fees
12 Dec - 13 Dec
Johnstone Mansion
Living area
Stay in this Unique SE Iowa Apt

Stay in this Unique SE Iowa Apt

Stay in this Unique SE Iowa Apt
Fort Madison
10.0 out of 10, Exceptional, (14)
"Would definately stay here agan."
United States
Christina
The price is AU$219
includes taxes & fees
23 Dec - 24 Dec
Stay in this Unique SE Iowa Apt
Fridge, microwave, oven, stovetop
Beautiful Riverview Apt Located in Downtown Fort Madison

Beautiful Riverview Apt Located in Downtown Fort Madison

Beautiful Riverview Apt Located in Downtown Fort Madison
Fort Madison
10.0 out of 10, Exceptional, (5)
"I was here for a couple weeks for work, and Rebecca was responsive with any questions, very friendly, and an excellent host!"
United States
Sam G.
The price is AU$316
includes taxes & fees
12 Dec - 13 Dec
Beautiful Riverview Apt Located in Downtown Fort Madison
Interior
Grand Victorian on the Mississippi

Grand Victorian on the Mississippi

Grand Victorian on the Mississippi
Fort Madison
9.8 out of 10, Exceptional, (22)
"The Grand Victorian is AMAZING!! The house is gorgeous and beautifully decorated. Everything was there that we needed, the area was peaceful and easy to access. Highly recommend staying here! "
United States
Andrea S.
The price is AU$649
includes taxes & fees
14 Dec - 15 Dec
Grand Victorian on the Mississippi
Interior
Johnston Mansion Bed and Breakfast price shown is Vrbo Mansion price

Johnston Mansion Bed and Breakfast price shown is Vrbo Mansion price

Johnston Mansion Bed and Breakfast price shown is Vrbo Mansion price
Keokuk
9.0 out of 10, Wonderful, (2)
"Beautiful place in lovely, walkable neighborhood near the Mississippi. The hosts couldn't have been more accommodating or kind."
United States
Kathryn C.
The price is AU$2,810
includes taxes & fees
18 Dec - 19 Dec
Johnston Mansion Bed and Breakfast price shown is Vrbo Mansion price
Fridge, microwave, oven, stovetop
Stay in Historic Downtown Keokuk

Stay in Historic Downtown Keokuk

Stay in Historic Downtown Keokuk
Keokuk
10.0 out of 10, Exceptional, (34)
"We always stay here when we are in town and It is always phenomenal! "
United States
Crystal M.
The price is AU$391
includes taxes & fees
12 Dec - 13 Dec
Stay in Historic Downtown Keokuk
In-room safe, desk, blackout curtains, soundproofing
Super 8 by Wyndham Keokuk

Super 8 by Wyndham Keokuk

Super 8 by Wyndham Keokuk
2.0 star property
Keokuk
7.6 out of 10, Good, (638)
"Enjoyed my stay"
United States
Paul
Super 8 by Wyndham Keokuk
Interior
Charming 2-bedroom cottage with WiFi, AC in enjoyable Fort Madison

Charming 2-bedroom cottage with WiFi, AC in enjoyable Fort Madison

Charming 2-bedroom cottage with WiFi, AC in enjoyable Fort Madison
Fort Madison
10.0 out of 10, Exceptional, (2)
"Very cute, well equipped small cottage. Street parking is on a bit of a hill...I was able to back my motorcycle into the small carport located on the alley. Quiet and comfortable."
United States
Joe E.
Charming 2-bedroom cottage with WiFi, AC in enjoyable Fort Madison
Fridge, microwave, oven, stovetop
Mayor's Manor - with everything you need in a homebase get away. Pet friendly.

Mayor's Manor - with everything you need in a homebase get away. Pet friendly.

Mayor's Manor - with everything you need in a homebase get away. Pet friendly.
Montrose
10.0 out of 10, Exceptional, (13)
"Very comfortable and convenient for our stay. Highly recommend."
United States
bob f.
Mayor's Manor - with everything you need in a homebase get away. Pet friendly.
Interior
3 Blocks from the Mississippi River in the Park-To-Park Historic District.

3 Blocks from the Mississippi River in the Park-To-Park Historic District.

3 Blocks from the Mississippi River in the Park-To-Park Historic District.
2.0 star property
Fort Madison
10.0 out of 10, Exceptional, (1)
3 Blocks from the Mississippi River in the Park-To-Park Historic District.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Lee County Hotel Reviews

Oak Hill Inn & Suites

Oak Hill Inn & Suites

10/10 Excellent
"The staff were very nice. "
James 3-night trip
Posted 3 days ago
Oak Hill Inn & Suites

Explore a world of travel with Expedia